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The net result of the process is that reducing equivalents from cytosolic NADH are transferred to the mitochondrial electron transport system

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Access this article Similar content being viewed by others Abbreviations ARE: Antioxidant response element ATP: Adenosine 5-triphosphate ASC: Apoptosis-associated speck-like protein containing a CARD bZIP: Basic-region leucine zipper CNC: Cap n collar CNS: Central nervous system DEM: Diethyl Maleate Gclc: Glutamate cysteine ligase catalytic subunit Gclm: Glutamate cysteine ligase regulatory subunit HO-1: Heme oxygenase-1 Keap1: Kelch-like ECH-associated protein 1 LPS: Lipopolysaccharide NF-B: Nuclear factor-B NLRP3: NLR family pyrin domain containing protein 3 Nqo1: NAD(P)H:quinone oxidoreductase 1 Nrf2: Nuclear factor-erythroid-2-related factor 2 PRR: Pattern recognition receptor ROS: Reactive oxygen species References Ahmed SM, Luo L, Namani A, Wang XJ (1863) Tang X (2017) Nrf2 signaling pathway: pivotal roles in inflammation

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